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Vitamin B12 requirements fluctuate throughout the life course, influenced by metabolic demand and physiological changes

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Also, since you need stomach acid to absorb B12, long-term use of acid-suppressing proton pump inhibitors (such as Nexium, etc.) can lead to B12 deficiency, as can chronic intestinal conditions such as Crohns disease, celiac disease, and intestinal parasites

Adipose SNAIL1 regulates lipolysis and lipid partitioning by suppressing adipose triacylglycerol lipase expression